Product name: Trioctyl Methyl Ammonium Chloride
Other names: Methyltrioctylammonium chloride, Aliquat 336
CAS number: 5137-55-3
Recommended use: Phase transfer catalyst, separation processes, extraction
Supplier contact: Manufacturer or distributor information with address, emergency phone number, email
Synonyms: N-Methyltrioctylammonium chloride, Aliquat 336
GHS classification: Skin irritant (Category 2), Eye irritant (Category 2A), Acute toxicity (oral, Category 4), Hazardous to the aquatic environment (Category 1)
Pictograms: Exclamation mark, Environmental hazard
Signal word: Warning
Hazard statements: Harmful if swallowed, causes skin and eye irritation, very toxic to aquatic life with long lasting effects
Precautionary statements: Avoid contact with skin and eyes, do not breathe vapors or mist, wash thoroughly after handling, avoid release to environment
Routes of exposure: Swallowing, skin contact, inhalation, eye contact
Chemical name: Trioctyl Methyl Ammonium Chloride
Synonyms: Aliquat 336, N-Methyl-N,N,N-trioctylammonium chloride
CAS number: 5137-55-3
EC number: 225-893-9
Purity: Over 95%
Impurities: Minor quantities of other quaternary ammonium salts
Molecular formula: C25H54ClN
Molecular weight: 404.16 g/mol
Inhalation: Move person to fresh air, keep at rest and comfortable, seek medical attention if feeling unwell
Skin contact: Remove contaminated clothing, wash skin with plenty of soap and water for at least 15 minutes, seek medical attention for irritation or burns
Eye contact: Rinse eyes cautiously with water for at least 15 minutes, remove contact lenses if present and easy, continue rinsing, get prompt medical advice
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical attention
Most important symptoms/effects: Burning sensation, redness, pain
Note to physician: Treat symptomatically, ensure airway management
Suitable extinguishing media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable extinguishing media: High volume water jet
Special hazards: Decomposes releasing toxic fumes of nitrogen oxides, carbon monoxide, hydrochloric acid
Firefighting procedures: Wear self-contained breathing apparatus, protective clothing, avoid breathing fumes, use water spray to cool containers
Flash point: Above 100°C
Explosion hazard: Product is not itself explosive; vapors in contact with high heat may form hazardous mixtures
Personal precautions: Use personal protective equipment, avoid inhalation and skin or eye contact, ensure adequate ventilation
Environmental precautions: Prevent release to drains, sewers, surface and ground waters; very toxic to aquatic life
Methods for containment: Absorb with inert material (sand, earth, or vermiculite), contain spill if safe
Cleanup methods: Collect and place in suitable closed containers for disposal; clean area with water, ventilate
Disposal: Follow regulations for hazardous chemical disposal
Precautions for safe handling: Use only in well-ventilated areas, avoid breathing vapors and dust, wash hands after handling, do not eat, drink, or smoke in work area
Safe storage conditions: Store in tightly closed containers in a cool, dry, well-ventilated area, away from heat and ignition sources
Incompatible materials: Strong oxidizing agents, acids, strong alkalis
Keep separate from: Food, feed, and incompatible chemicals
Specific storage requirements: Keep containers upright, label clearly, check regularly for leaks
Engineering controls: Use local exhaust ventilation where possible, provide safety shower and eyewash station
Personal protective equipment (PPE):
Gloves (nitrile or neoprene), chemical safety goggles, lab coat or apron, suitable protective footwear
Respiratory protection: Use approved respirator in case of inadequate ventilation
Exposure limits: No OSHA, ACGIH, or other specific exposure limits established
Hygiene measures: Wash hands, face, and exposed skin thoroughly after handling, remove contaminated clothing
Appearance: Colorless to pale yellow oily liquid
Odor: Faint, ammoniacal
Odor threshold: Not available
pH: Slightly basic (in aqueous solution)
Melting point: Softens at room temperature, solid below 15°C
Boiling point: Decomposes above 300°C
Flash point: Above 100°C
Evaporation rate: Not determined
Flammability: Not highly flammable
Vapor pressure: Very low
Density: 0.88 – 0.91 g/cm³ at 20°C
Solubility: Insoluble in water, very soluble in alcohols, benzene, and other organic solvents
Partition coefficient (Log Kow): High (likely > 4)
Auto-ignition temperature: Not determined
Decomposition temperature: Decomposes above 300°C
Viscosity: Viscous liquid at room temperature
Chemical stability: Stable under recommended storage conditions
Reactivity: Not highly reactive under normal environmental or handling conditions
Hazardous reactions: Reacts with strong oxidizers, acids may cause decomposition
Decomposition products: Hydrochloric acid, carbon monoxide, nitrogen oxides
Conditions to avoid: High temperatures, direct sunlight, sources of ignition
Polymerization: Will not occur
Routes of entry: Inhalation, skin, eye, ingestion
Acute toxicity: LD50 (oral, rat): 1200 – 1600 mg/kg
Skin corrosion/irritation: Causes irritation
Eye damage/irritation: Causes irritation
Respiratory tract irritation: Vapors or dust may irritate respiratory tract
Chronic effects: Prolonged or repeated exposure may cause skin dryness or cracking
Sensitization: No data
Carcinogenicity: Not listed by IARC, NTP, OSHA
Mutagenicity: No significant data
Reproductive toxicity: No significant data
Other information: Harmful if swallowed, may cause gastrointestinal distress, dizziness, weakness
Toxicity to aquatic life: Very toxic to aquatic organisms (Fish LC50 < 1 mg/L, Daphnia EC50 < 1 mg/L)
Biodegradability: Not readily biodegradable (persists in the environment)
Bioaccumulative potential: High (due to high log Kow, may accumulate in aquatic organisms)
Mobility in soil: Low (binds to soil, poor water solubility)
PBT/vPvB assessment: Meets criteria for persistent, bioaccumulative, and toxic
Other effects: Disrupts aquatic ecosystems, avoid release to natural waters
Waste treatment methods: Must treat as hazardous waste, incinerate in licensed facility, do not pour down the drain
Disposal of product: Collect in sealed containers and send to licensed chemical disposal company
Disposal of packaging: Triple rinse, destroy or offer recycling to approved handler, do not reuse containers
Regulatory information: Waste codes per local, regional, and national regulations
Special precautions: Avoid contact with substances incompatible with ammonium compounds
UN Number: 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Trioctyl methyl ammonium chloride)
Transport hazard class: 9 (Miscellaneous dangerous substances)
Packing group: III
Environmental hazards: Marine pollutant
Transport labels: Class 9 (Miscellaneous)—environmental hazard symbol
Special precautions for user: Follow all DOT, IMDG, ICAO/IATA transport regulations, carry emergency spill procedures
TSCA: Listed
REACH: Registered as a phase-in substance
SARA 313: Not listed
California Proposition 65: Not listed
OSHA: Hazardous by definition
EU Classification: Harmful (Xn), Irritant (Xi), Dangerous for the environment (N)
Labeling standards: GHS as per OSHA Hazard Communication Standard
Other local/national regulations: Subject to chemical safety and environmental protection regulations as hazardous material
