Product Name: Tetrapropylammonium Chloride
Chemical Formula: C12H28ClN
Synonyms: N,N,N-Tri-n-propylpropan-1-aminium chloride
CAS Number: 136-94-7
Recommended Use: Research purposes, industrial manufacturing, laboratory reagent, phase transfer catalyst
Supplier Information: Manufacturer address, technical contact number, and emergency phone for consultation
Classification: Eye irritation, Skin irritation, Acute toxicity (oral)
GHS Label Elements: Signal word: Warning; Hazard pictograms: Exclamation mark
Hazard Statements: Causes eye irritation, May cause respiratory irritation, Harmful if swallowed, Causes skin irritation
Precautionary Statements: Avoid contact with eyes, Avoid inhaling dust or vapor, Wear protective equipment, Do not eat, drink or smoke while using
Potential Health Effects: Short-term exposure can cause redness, burning sensation, coughing, stomach discomfort
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Chemical Name: Tetrapropylammonium Chloride
Concentration: >98%
Impurities: Negligible, below reporting threshold
Molecular Weight: 221.82 g/mol
Inhalation: Move person to fresh air, seek immediate medical attention for persistent discomfort, loosen tight clothing
Skin Contact: Remove contaminated clothing, wash with soap and water for several minutes, consult a physician if irritation persists
Eye Contact: Flush with plenty of water for at least 15 minutes, keep eyelids open, remove contact lenses if possible, get medical help
Ingestion: Do not induce vomiting, rinse mouth, drink water if conscious, seek physician care immediately
Important Information for Doctors: Treat symptomatically, monitor for respiratory and gastrointestinal symptoms, support vital functions as necessary
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet might spread spilled material
Fire Hazards: Emits toxic fumes (hydrogen chloride, nitrogen oxides, carbon oxides) under combustion
Protective Equipment: Wear self-contained breathing apparatus, chemical protective clothing, keep upwind of fire
Special Procedures: Evacuate area, prevent contaminated runoff into drains, cool containers exposed to flames with water spray
Personal Precautions: Use appropriate personal protective equipment, ventilate area, avoid breathing dust
Environmental Precautions: Prevent further leakage or spillage if safe to do so, do not allow substance to enter drains or water courses
Cleaning Measures: Collect spilled solid by sweeping or shoveling into appropriate waste container, decontaminate area with water and detergent
Emergency Procedures: Isolate hazard area, remove all sources of ignition, restrict access until clean-up is complete
Handling: Use in well-ventilated area, avoid generation of dust, handle with chemical resistant gloves and eye protection, do not ingest or inhale
Storage: Store in tightly closed container, away from sources of heat, sparks, and flames, keep material in a dry, cool, well-ventilated location, segregate from strong acids and oxidizing agents
Special Notes: Label storage containers, keep away from incompatible materials, implement spill control and secondary containment plans, limit access to authorized personnel
Engineering Controls: Use fume hoods, provide eyewash stations and safety showers, ensure proper ventilation for confined spaces
Personal Protective Equipment: Chemical splash goggles, chemical-resistant gloves (nitrile, neoprene), lab coat or appropriate clothing, NIOSH-approved respirator for airborne concentrations above permissible limits
Occupational Exposure Limit: No specific established local or international exposure limits
Workplace Practices: Wash hands after handling, refrain from eating, drinking or smoking during use, change contaminated clothing promptly
Appearance: White to pale yellow crystalline solid
Odor: Slight, characteristic amine odor
Odor Threshold: Not established
pH (1% solution): Slightly basic, approximately 8.5–9.5
Melting Point/Freezing Point: Decomposes above 220°C without melting
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable under standard conditions
Evaporation Rate: Not available
Flammability: Not classified as flammable
Vapor Pressure: Not measurable at room temperature
Solubility: Soluble in water, methanol; very slightly soluble in acetone, chloroform
Vapor Density: Not applicable
Relative Density: Approximate value 1.1 g/cm³
Partition Coefficient: Not established
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: Above 220°C, releases toxic gases
Viscosity: Not applicable for solids
Chemical Stability: Stable under standard laboratory conditions, hygroscopic
Reactivity: Reacts with strong oxidizing agents
Conditions to Avoid: High humidity, strong heat, incompatible substances
Incompatible Materials: Strong acids, oxidizing agents, peroxides
Hazardous Decomposition: Hydrogen chloride, nitrogen oxides, carbon oxides, short-chain alkyl amines
Polymerization: No hazardous polymerization expected under normal conditions
Acute Toxicity: Harmful if swallowed; estimated rat oral LD50 ranges from 400–800 mg/kg
Skin Corrosion/Irritation: Can provoke redness or rash after contact
Eye Damage/Irritation: Risk of temporary discomfort or inflammation
Respiratory Effects: May cause cough or throat irritation; large exposures risk pulmonary symptoms
Sensitization: Not classed as a skin sensitizer though sensitization remains possible with chronic exposure
Chronic Effects: Not enough studies for detailed profiling
Carcinogenicity: Not listed by IARC, NTP or OSHA
Mutagenicity: No available test data
Reproductive Toxicity: No evidence from existing case reports or literature
Ecotoxicity: High concentrations pose moderate risk to aquatic organisms
Aquatic Toxicity: LC50 (fish, 96 h) expected at 10–100 mg/L; avoid release to natural waters
Persistence and Degradability: Not readily biodegradable
Bioaccumulation Potential: Low due to high water solubility
Mobility in Soil: Migrates in soil due to solubility, can contaminate groundwater
Other Adverse Effects: May disrupt microbial processes if released in bulk quantities
Disposal Methods: Dispose as hazardous chemical waste, use licensed chemical incineration or supervised landfill according to local regulations
Container Disposal: Triple rinse empty containers, puncture and offer for recycling or disposal at approved site
Environmental Precaution: Avoid releasing to sewers, drains, water bodies or open land
Precautions: Consult local, regional, and national guidelines for management of chemical waste
Contaminated Packaging: Collect and manage as hazardous waste; do not reuse packaging
UN Number: Not regulated as a dangerous good by current ADR/RID, IMDG, or IATA rules
Proper Shipping Name: Not classified as hazardous for transport
Hazard Class: Not assigned
Packing Group: Not required
Environmental Hazards: Not regulated for marine pollutant status
Special Transport Precautions: Ships in sealed, clearly marked containers, segregate from foodstuffs and strong acids
Inventory Status: Listed for use in major chemical inventories (TSCA, EINECS/ELINCS, DSL, AICS, ENCS)
Workplace Labeling: Hazard class and precautionary labels apply per GHS rules
REACH Status: Pre-registered or registered for limited uses under European law
OSHA: Not specifically regulated as a hazardous material; general duty to handle as potentially hazardous
SARA Title III / CERCLA: Does not appear on SARA Extremely Hazardous Substances list; not subject to federal reportable quantity requirements
State/Local Regulations: Check for any state-specific chemical controls for storage, handling, or emissions
Other Standards: Subject to handling standards in facilities using chemicals; periodic review recommended according to workplace safety audits
