Product Name: Tetramethylammonium Chloride
Chemical Formula: C4H12NCl
Synonyms: Quaternary ammonium salt, TMA-Cl
CAS Number: 75-57-0
Recommended Use: Laboratory reagent, chemical synthesis, electronics industry
Manufacturer Contact: [Company details provided on separate documentation]
Classification: Acute toxicity (oral, dermal), skin and eye irritation, target organ toxicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed, causes skin irritation, may cause respiratory irritation, severe eye damage
Precautionary Statements: Avoid breathing dust, wash hands after handling, use proper ventilation, wear protective gloves and goggles, store locked up
Potential Health Effects: Inhalation leads to coughing, dizziness; skin contact causes redness; eye exposure brings severe discomfort and visual disturbance; ingestion results in nausea, abdominal pain, and potential neurological symptoms
Pictograms: Exclamation mark, health hazard
Chemical Name: Tetramethylammonium Chloride
Concentration: ≥ 98%
Other Components: Trace moisture (<0.5%)
Impurities: None known at standard manufacturing purity
Molecular Weight: 109.61 g/mol
Hazardous Ingredients: Tetramethylammonium ion (C4H12N+), chloride ion (Cl-)
Inhalation: Move affected individual to fresh air, check for breathing and provide oxygen if available, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, wash contacted skin with soap and water for at least 15 minutes, medical attention required if irritation develops
Eye Contact: Rinse eyes with water for several minutes holding eyelids open, remove contact lenses if present, immediate ophthalmological evaluation
Ingestion: Rinse mouth thoroughly, do not induce vomiting, offer water to drink, immediate medical assistance needed
Symptoms to Watch: Coughing, headache, irritation, disorientation, burns
Most Important Routes of Exposure: Oral, dermal, ocular, respiratory
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam, water spray
Hazardous Combustion Products: Methylamine gases, hydrogen chloride, nitrogen oxides, carbon monoxide
Firefighting Instructions: Wear self-contained breathing apparatus, protective clothing, avoid breathing smoke, move containers from fire area if safe
Specific Hazards: Corrosive vapors likely, risk of pressure build-up in sealed containers under intense heat
Explosion Data: Non-explosive under normal conditions, may decompose releasing toxic fumes
Personal Precautions: Put on protective equipment—gloves, eye protection, face shield, respirator if necessary
Environmental Precautions: Prevent entry into sewers, surface water, or soil, contain with sand or absorbent material
Spill Cleanup Methods: Sweep up solid material using wet methods or a HEPA vacuum, transfer to a suitable waste container, ventilate the area, wash spill site after removal
Special Cleanup: Neutralize residues with dilute acid or base depending on pH
Disposal: Refer to local hazardous waste guidelines for disposal of contaminated materials
Handling: Use only in chemical fume hood, avoid inhalation or direct contact with skin and eyes, prevent aerosol or dust formation, avoid ingestion, never pipette by mouth
Storage: Store in tightly closed container in a cool, dry, well-ventilated area, keep away from incompatible substances such as oxidizing agents or strong acids, keep away from heat sources and direct sunlight, secure against unauthorized access
Hygiene Practices: Wash thoroughly after handling, do not eat, drink, or smoke in storage or handling areas
Occupational Exposure Limits: No established OSHA/ACGIH limits, minimize exposure as a precaution
Engineering Controls: Local exhaust ventilation, eye wash station, safety shower
Personal Protective Equipment: Nitrile gloves, safety goggles with side shields, lab coat or chemical-resistant apron, NIOSH-approved respirator for powder or aerosol exposure
Environmental Protection: Prevent run-off to waterways, ensure procedures for limiting exposure extend to drainage and waste systems
Appearance: White to colorless crystalline powder
Odor: Mild, amine-like
Melting Point: 242–247°C
Boiling Point: Decomposes before boiling
Solubility: Freely soluble in water, ethanol, methanol
Density: 1.158 g/cm³ at 25°C
pH: 6.0–7.0 (5% solution in water)
Vapor Pressure: Negligible at standard conditions
Partition Coefficient (Log Kow): Not established for the compound
Evaporation Rate: Not applicable
Flash Point: Not flammable
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: Above 250°C with toxic fume emission
Chemical Stability: Stable under recommended conditions and temperatures
Reactivity: Reacts with strong oxidizers or acids producing toxic gases
Hazardous Reactions: Sudden decomposition possible upon excessive heating or in presence of incompatible chemicals
Incompatible Materials: Oxidizing agents, strong acids, alkali metals
Hazardous Decomposition Products: Methylamine, nitrogen oxides, hydrochloric acid fumes, carbon monoxide/carbon dioxide
Storage Stability: Shows no significant shelf-life reduction under cool, dry, tightly capped storage
Routes of Exposure: Oral, dermal, inhalation, ocular
Acute Toxicity (oral/rat): LD50 25–50 mg/kg
Acute Toxicity (dermal/rabbit): Estimated LD50 500 mg/kg
Skin Irritation: Causes moderate to severe irritation, possible chemical burns
Eye Damage: Risk of severe irritation and vision impairment
Inhalation: Can cause respiratory irritation and symptoms of toxicity at high doses, sensitization possible
Chronic Effects: Long-term or repeated exposure may damage nervous system, kidneys, or liver
Carcinogenicity: Not classified by IARC, NTP, or EPA
Reproductive Toxicity: No known evidence of reproductive harm at exposure levels typical for laboratory conditions
Symptoms: Dizziness, nausea, abdominal pain, motor impairment
Ecotoxicity: Harmful to aquatic life, risk of acute toxicity in water invertebrates and fish
Persistence and Degradability: Degrades slowly in natural conditions, some potential for bioaccumulation
Mobility in Soil: High mobility due to solubility, potential for groundwater contamination
Bioaccumulative Potential: Data not fully established, risk considered low for typical environmental concentrations
Other Adverse Effects: No evidence for ozone depletion or long-range ecological harm, but localized impact from spills is significant
Waste Handling: Collect and package residues in appropriately labeled chemical waste containers
Regulatory Status: Classified hazardous under RCRA, local disposal laws apply
Disposal Methods: Incinerate in approved chemical incinerator with afterburner and scrubber, consult licensed waste disposal company
Contaminated Packaging: Handle as hazardous waste, empty containers should be triple rinsed and marked for specialized disposal
Avoid Release: Do not discharge to surface waters, groundwater or sewers
UN Number: 2811
Shipping Name: Toxic solid, organic, n.o.s. (Tetramethylammonium chloride)
Hazard Class: 6.1 (Toxic substance)
Packing Group: II
Label: Toxic (skull and crossbones symbol required)
Maritime Transport: IMDG regulated, not marine pollutant
Air Transport: IATA/ICAO regulated, handle as toxic solid
Special Precautions for Transport: Avoid mechanical shock, secure packaging; in case of spill during transport, follow ERG Guide 151
TSCA Status: Listed in US Toxic Substances Control Act inventory
REACH Status: Registered in accordance with European Union REACH regulations
SARA Title III: Subject to reporting under CERCLA for releases above RQ, not on Section 313 list
Canada DSL/NDSL: On Domestic Substances List
OSHA Hazard Classification: Acute toxicity, skin corrosion/irritation, serious eye damage/irritation
Labeling Requirements: Compliant with GHS, CLP, and OSHA HCS
Other Regulatory Info: State and local environmental regulations may apply
