Product Name: Tetramethylammonium Bromide
Synonyms: Tetrakis(methyl)ammonium bromide
Chemical Formula: C4H12BrN
CAS Number: 64-20-0
Recommended Use: Laboratory chemical, research, and fine chemical production
Supplier: Refer to label or invoice for current contact information
Emergency Contact: National Poison Center or local emergency authorities
Classification: Irritant to skin, eyes, and respiratory tract
Globally Harmonized System (GHS): Eye Irritation (Category 2A), Skin Irritation (Category 2), Acute Toxicity Oral (Category 4)
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, harmful if swallowed
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust; wash hands after handling; wear protective gloves and eye protection; do not eat, drink, or smoke while using this product
Chemical Name: Tetramethylammonium Bromide
Purity: >98%
CAS Number: 64-20-0
EC Number: 200-583-2
Molecular Weight: 194.06 g/mol
Impurities: Typically none of toxicological significance under standard laboratory conditions
Inhalation: Move affected person to fresh air immediately; if symptoms like coughing or shortness of breath persist, seek medical attention
Skin Contact: Flush exposed skin with plenty of water for at least 15 minutes; remove contaminated clothing and wash before reuse
Eye Contact: Rinse eyes cautiously with water for several minutes, lifting upper and lower eyelids; remove contact lenses if present and easy to do; seek medical attention if irritation continues
Ingestion: Rinse mouth thoroughly with water; do not induce vomiting; seek medical advice immediately
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, or alcohol-resistant foam
Methods: Use water jet only to cool containers
Specific Hazards: Releases toxic fumes including nitrogen oxides and hydrogen bromide during combustion
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Advice for Responders: Avoid inhalation of combustion byproducts; isolate hazard area; prevent runoff from fire-fighting measures into drains or natural water systems
Personal Precautions: Wear appropriate personal protective equipment including gloves, laboratory coat, goggles, and particulate respirator if dust is generated
Environmental Precautions: Prevent product from entering waterways, drains, and soil
Methods for Clean-Up: Sweep up spilled material carefully to avoid generating airborne dust; place in suitable container for disposal; ventilate area and wash spill site once cleanup is complete
Safe Handling: Handle in a well-ventilated area utilizing chemical fume hood; minimize dust formation and contact with skin and eyes; avoid inhaling dust or vapor
Storage Conditions: Store in a cool, dry, well-ventilated place, tightly sealed; keep away from incompatible substances like oxidizing agents and strong acids
Incompatible Materials: Avoid contact with strong oxidizers; chemical may react vigorously with acids to release toxic gases
Engineering Controls: Use local exhaust ventilation or work in a fume hood
Personal Protective Equipment (PPE): Safety goggles, laboratory coat, chemical-resistant gloves (such as nitrile or neoprene), use particulate respirator where dust levels are high
Respiratory Protection: Use approved NIOSH/MSHA respirators when necessary
Hygiene Measures: Wash thoroughly after handling; do not eat, drink, or smoke in areas where this chemical is used; launder clothing before reuse
Appearance: White crystalline powder
Odor: Odorless
Melting Point: About 230°C (decomposes)
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water and alcohol
Density: 1.389 g/cm3 at 20°C
pH: Slightly alkaline in solution
Vapor Pressure: Negligible
Partition Coefficient (n-octanol/water): Not determined
Flash Point: Not flammable
Chemical Stability: Stable under ordinary conditions of use and storage
Hazardous Reactions: Reacts with strong oxidizing agents
Conditions to Avoid: Exposure to moisture, high temperatures, and incompatible materials
Decomposition Products: Nitrogen oxides, methylamines, hydrogen bromide (HBr), carbon oxides under fire conditions
Polymerization: Product does not polymerize under normal conditions
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: LD50 (oral, rat): around 480 mg/kg; harmful if ingested
Skin Corrosion/Irritation: Causes irritation on contact
Eye Damage/Irritation: Induces serious eye irritation; symptoms include redness, pain, tearing
Chronic Effects: Data on chronic toxicity are limited; repeated exposure can result in skin and respiratory tract sensitization
Carcinogenicity: No component present at levels greater than or equal to 0.1% identified as probable, possible, or confirmed human carcinogen by IARC, NTP, or OSHA
Ecotoxicity: Data limited; avoid discharge to the environment
Aquatic Toxicity: May be harmful to aquatic life; no established LC50 values but minimal information points to moderate toxicity potential
Persistence/Degradability: Not rapidly biodegradable; can persist if released
Bioaccumulation Potential: Low, based on chemical structure
Mobility in Soil: Moderate water solubility suggests some movement through soil, but binding likely to organic material
Disposal Methods: Dispose of contents and container in accordance with local, regional, national, and international regulations; use licensed chemical waste disposal contractor
Contaminated Packaging: Rinse container before disposal; absorb rinsing with inert material and treat as chemical waste
Special Precautions: Prevent release into drains or environment; do not dispose of with household garbage; comply with all applicable waste disposal regulations
UN Number: Not regulated for ground, air, or sea transportation under current international regulations for this quantity and form
Proper Shipping Name: Not dangerous goods
Transport Hazard Class: None assigned
Packing Group: None
Environmental Hazards: Not classified as marine pollutant
Special Precautions for User: Keep containers well-sealed; transport upright and securely
Regulatory Information: Check national and local guidelines for any quantity thresholds triggering notification or reporting
OSHA: Chemical listed; not classified as hazardous per OSHA Hazard Communication Standard
TSCA Status: Appears on the Toxic Substances Control Act (TSCA) Inventory
REACH: May be subject to registration requirements; consult European Chemicals Agency
Other Inventories: Listed in key chemical inventories in the United States, Canada, Europe, and Asia
Labeling Requirements: Comply with GHS/CLP labeling requirements based on hazard classification
Additional Information: Always reference the latest regulatory documents as regulations and hazardous classifications can change over time
