Product Name: Tetrabutylammonium Bromide
Chemical Formula: C16H36BrN
CAS Number: 1643-19-2
Molecular Weight: 322.37 g/mol
Synonyms: TBAB, Tetrabutylammonium bromide, N,N,N-Tributyl-1-butanaminium bromide
Application: Phase transfer catalyst, laboratory reagent, chemical synthesis
Supplier: Refer to the original packaging for supplier and emergency contact
Recommended Use: Industrial/Research use only
Classification: Skin irritation (Category 2), Eye irritation (Category 2A), Acute toxicity (Category 4, oral)
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes skin and eye irritation.
Precautionary Statements: Avoid breathing dust. Wash hands thoroughly after handling. Wear protective gloves, clothing, and eye protection. If swallowed: Rinse mouth. Call poison center if unwell. If on skin: Wash with plenty of soap and water. If in eyes: Rinse cautiously with water for several minutes.
Other Hazards: No data available for dust explosion, may cause irritation to respiratory system if inhaled as powder.
Chemical Name: Tetrabutylammonium Bromide
Purity: ≥98%
Chemical Family: Quaternary ammonium compound
Impurities: Typically less than 2%, may include trace organics from synthesis
Physical State: Crystalline solid or powder
General Advice: Move person away from exposure source. Keep under medical supervision.
Inhalation: Move to fresh air, keep victim warm and at rest. Seek immediate medical attention if symptoms develop.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water for at least 15 minutes. Seek medical attention if irritation persists.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rising. Get medical attention.
Ingestion: Rinse mouth thoroughly with water. Never give anything by mouth to an unconscious person. Do not induce vomiting. Seek medical help.
Notes to Physician: Treat symptomatically and supportively.
Flammability: Not readily flammable but may decompose and produce toxic fumes. Dust may form explosive mixtures with air under rare circumstances.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Special Hazards: Burning may release toxic and irritating fumes including hydrogen bromide, nitrogen oxides, carbon oxides.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear.
Cool containers: Use water to keep nearby containers cool in the event of fire.
Unusual Hazards: Run-off from fire control may cause water pollution.
Personal Precautions: Wear suitable protective clothing, gloves and eye/face protection. Avoid dust formation.
Environmental Precautions: Prevent entry into sewers, waterways or confined spaces. Contain spill using inert absorbent material.
Cleanup Methods: Sweep or scoop up spilled material and place in properly labeled containers for disposal. Wash spill site after material pickup is complete.
Decontamination: Clean surfaces thoroughly to remove residues.
Handling: Avoid contact with skin, eyes, and clothing. Prevent dust generation and buildup. Use only in well-ventilated areas.
Storage: Store in tightly closed containers in a cool, dry, and well-ventilated place. Keep away from incompatible materials such as strong oxidizing agents.
Incompatible Materials: Strong acids, strong bases, oxidizers.
Safe Storage Temperature: Ambient temperature (room temperature preferred); avoid moisture exposure.
Special Requirements: Use corrosion-resistant containers.
Exposure Limits: No established workplace exposure limits1
Engineering Controls: General exhaust ventilation recommended. Local exhaust for dust control.
Personal Protective Equipment:
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH (1% solution): 6 to 8
Melting Point: 101-104°C
Boiling Point: Decomposes
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not flammable
Vapor Pressure: Negligible
Vapor Density: Not available
Relative Density: 1.04-1.06 g/cm³
Solubility: Soluble in water, alcohol, acetone
Partition Coefficient (n-octanol/water): Not determined
Auto-Ignition Temperature: Not available
Decomposition Temperature: Decomposes at elevated temperature
Viscosity: Not available
Chemical Stability: Stable under recommended storage conditions.
Possibility of Hazardous Reactions: No dangerous reactions known under normal conditions.
Conditions to Avoid: Excessive heat, moisture, strong oxidizers, strong acids.
Incompatible Materials: Strong oxidizing agents, acids, bases.
Hazardous Decomposition Products: May form hydrogen bromide, nitrogen oxides, carbon monoxide, and carbon dioxide.
Routes of Exposure: Ingestion, inhalation, skin and eye contact
Acute Toxicity: Harmful if swallowed. May cause gastro-intestinal disturbances. Irritating to skin and eyes.
LD50 (oral, rat): 450 mg/kg
Skin Corrosion/Irritation: Causes skin irritation on contact.
Eye Damage/Irritation: Causes eye irritation. May result in redness, tearing, pain.
Respiratory Sensitization: May cause respiratory tract irritation if inhaled as dust.
Skin Sensitization: Not expected based on available data.
Chronic Toxicity: No evidence of chronic effects at low exposures. Prolonged exposure may aggravate pre-existing eye, skin, and respiratory conditions.
Carcinogenicity: Not listed by IARC, NTP, OSHA.
Mutagenicity: No evidence found.
Reproductive toxicity: No known effects on reproduction or development based on animal data.
Environmental Toxicity: Expected to be toxic to aquatic organisms. May cause adverse long-term effects in the aquatic environment.
Persistence and Degradability: Slow biodegradation in the environment.
Bioaccumulative Potential: Not expected to bioaccumulate significantly due to high water solubility.
Mobility in Soil: High mobility due to water solubility.
Other Adverse Effects: Avoid release to the environment. Specialized disposal handling needed for bulk quantities.
Waste Handling: Dispose of in accordance with local, regional, national, and international regulations. Avoid disposing into drains.
Unused Product: Collect and deliver to hazardous waste collection point.
Contaminated Packaging: Empty containers should be collected and delivered to appropriate waste station for recycling or disposal.
Precautions: Use personal protective equipment during waste handling.
Recommended Disposal Method: Chemical waste incineration or approved landfill site, according to environmental authority guidelines.
UN Number: Not regulated for transport.
Transport Hazard Class: Not classified as hazardous.
Packing Group: Not applicable
Hazard Label: Not required
Marine Pollutant: Not classified
Special Precautions: Keep in tightly closed containers during transport to avoid spills and exposure. Ensure upright storage and secure packaging.
DOT, IATA, IMDG: Not regulated
EU Regulation: Not listed under REACH Annex XIV or candidate list. Under Regulation (EC) No 1272/2008, classified as harmful/irritant.
US Regulation: Not a controlled substance under SARA, CERCLA, TSCA (present). Not regulated as hazardous by OSHA.
Canada WHMIS: D2B (Toxic material causing other toxic effects, irritant).
Labeling Requirements: Warning. Wear suitable protective clothing, avoid skin and eye contact.
Other Regulations: Always follow state and local guidelines, as requirements can change.
Product Restrictions: For industrial and laboratory use only. Not intended for food, drug, or household use.
